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Clinical trials for Blood Substitute

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    25 result(s) found for: Blood Substitute. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2010-021797-10 Sponsor Protocol Number: TIS2012 Start Date*: 2012-01-19
    Sponsor Name:VU university medical center
    Full Title: A phase II randomized multicenter study on efficacy and safety of cultured autologous skin (Tiscover®) and acellular dermal matrix (AS210) in chronic (arterio-)venous ulcers
    Medical condition: The autologous cultured skin substitute (Tiscover) or acellular donor dermis (AS210) is applied to patients with chronic (arterio-) venous leg wounds.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-001434-16 Sponsor Protocol Number: 3D_CHB/collacone Start Date*: 2016-03-30
    Sponsor Name:Universitätsmedizin Greifswald, KöR
    Full Title: A method for measuring volume changes of the alveolar ridge during dental implantation using 3D scanning
    Medical condition: alveolar ridge atrophy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10074846 Alveolar bone resorption PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-004605-27 Sponsor Protocol Number: Occhuiosecco Start Date*: 2012-11-05
    Sponsor Name:AZIENDA OSPEDALIERA ARCISPEDALE S. MARIA NUOVA
    Full Title: Study Prospective Randomized Controlled Double-Blind: Comparison of tear substitute (Siccafluid) and Autologous Serum in Dry Eye Disease
    Medical condition: Dry eye disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004853 10018728 Gritty eyes LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-018450-12 Sponsor Protocol Number: 706079098 Start Date*: 2010-08-18
    Sponsor Name:Agneta Blanck Olerup
    Full Title: Optimising pain control after caesarean section - an evaluation if oxycodone can replace morphine and low potency opioids postoperatively.
    Medical condition: Pain management after elective cesarean section.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10036276 Postoperative analgesia LLT
    Population Age: Newborns, Under 18, Adults Gender: Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003683-54 Sponsor Protocol Number: OSHO #76 Start Date*: 2008-06-18
    Sponsor Name:GMIHO Gesellschaft für medizinische Innovation/Hämatologie und Onkologie mbH
    Full Title: Prospektive, offene, randomisierte, multizentrische Studie zur Effektivität von Palifermin in der Prophylaxe der Mukositis nach allogener Stammzelltransplantation mit myeloablativer Granzkörperbest...
    Medical condition: Patients suffering from leukemia (acute or chronic), receiving allogenic blood stem cell transplantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2021-005374-26 Sponsor Protocol Number: ECAELEV21 Start Date*: 2022-08-18
    Sponsor Name:OMEQUI coordinator
    Full Title: Efficacy of platelet- and leukocyte-rich fibrin (L-PRF) in reducing healing time in sinus lift combined with deproteinized bovine mineralized bone (DBBM): randomized clinical trial.
    Medical condition: If the application of L-PRF with respect to the use of DBBM shows that there are differences in the percentage of new bone between the LPRF group and the control group at 4 and 6 months
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001725-25 Sponsor Protocol Number: RSA-HIP220306 Start Date*: 2007-08-09
    Sponsor Name:GREATER GLASGOW HEALTH BOARD
    Full Title: REVISION HP REPLACEMENT - ACETABULAR IMPACTION GRAFTING - A RADIOSTEREOMETRIC COMPARISON BETWEEN FRESH FROZEN ALLOGRAFT AND MARROW-DEPLETED BONE WITH CALCIUM PHOSPHATE PLUS OR MINUS BONE MORPHOGENI...
    Medical condition: REVISION HIP REPLACEMENT
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057128 Revision of hip arthroplasty LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-002190-10 Sponsor Protocol Number: UCDCRC/20/03 Start Date*: 2021-02-05
    Sponsor Name:University College Dublin
    Full Title: Coagulopathy of COVID-19: A Pragmatic Randomized Controlled Trial of Therapeutic Anticoagulation versus Standard Care as a Rapid Response to the COVID-19 Pandemic (RAPID COVID COAG)
    Medical condition: Coagulopathy of COVID-19 appears to afflict approximately 20% of patients with severe COVID-19 and is associated with need for critical care and death. COVID-19 coagulopathy is characterized by ele...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: View results
    EudraCT Number: 2020-001571-32 Sponsor Protocol Number: APHP200406 Start Date*: 2020-04-15
    Sponsor Name:Assistance Publique Hôpitaux de Paris
    Full Title: Low dose of IL-2 In Acute respiratory DistrEss syndrome related to COVID-19 LILIADE-COVID
    Medical condition: COVID-19
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-001726-99 Sponsor Protocol Number: P17/15 Start Date*: 2021-07-12
    Sponsor Name:Centre Hospitalier de Versailles
    Full Title: Comparison of corticosteroids versus placebo on duration of ventilatory support during severe acute exacerbations of COPD patients in the intensive care unit: a multicentre randomized controlled tr...
    Medical condition: Severe acute exacerbations of Chronic Obstructive Pulmonary Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-005185-18 Sponsor Protocol Number: HEPA-CRV431-207 Start Date*: 2022-07-27
    Sponsor Name:Hepion Pharmaceuticals, Inc.
    Full Title: ASCEND-NASH: A PHASE 2B, RANDOMIZED, MULTI-CENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF CRV431 IN ADULT SUBJECTS WITH NONALCOHOLIC STEATOHEPATITIS AND ADVAN...
    Medical condition: NONALCOHOLIC STEATOHEPATITIS AND ADVANCED LIVER FIBROSIS
    Disease: Version SOC Term Classification Code Term Level
    24.1 100000004871 10086370 NASH with fibrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) IT (Prematurely Ended) ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-004975-37 Sponsor Protocol Number: LIMIT Start Date*: 2021-09-06
    Sponsor Name:Hamilton Health Sciences through the Population Health Research Institute
    Full Title: Low INR to Minimize bleeding with mechanical valves Trial
    Medical condition: Treatment with a Vitamin K Antagonist due to having a mechanical heart valve.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Ongoing) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-003652-32 Sponsor Protocol Number: ISA101b-OPC-03-19 Start Date*: 2021-04-13
    Sponsor Name:ISA Therapeutics B.V.
    Full Title: A Phase II Study of cemiplimab, an anti-PD-1 monoclonal antibody, and ISA101b vaccine in patients with recurrent/metastatic HPV16- positive Oropharyngeal Cancer who have experienced disease progres...
    Medical condition: Recurrent/metastatic HPV16- positive Oropharyngeal Cancer (OPC)
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10031098 Oropharyngeal cancer recurrent PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) BE (Completed) CZ (Completed) ES (Ongoing) IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-004052-15 Sponsor Protocol Number: 202000570 Start Date*: 2021-11-24
    Sponsor Name:University Medical Center Groningen
    Full Title: ImmunoPET imaging with 89Zr-DFO-REGN3767 in patients with advanced solid cancer prior to and during treatment with cemiplimab with or without platinum-based chemotherapy
    Medical condition: Patients with metastatic solid tumors, where clinical data has shown a rationale for ICI therapy with or without platinum-based chemotherapy, will be included in this study.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003459-31 Sponsor Protocol Number: 2016/816 Start Date*: 2016-10-10
    Sponsor Name:Helse Bergen, Haukeland University Hospital
    Full Title: Treatment of patients with advanced breast cancer harboring TP53 mutations with dose-dense cyclophosphamide - the p53 trial
    Medical condition: Locally advanced breast cancer and metastatic breast cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-001947-28 Sponsor Protocol Number: T2017-002 Start Date*: 2019-06-11
    Sponsor Name:Therapeutic Advances in Childhood Leukemia Consortium (TACL)
    Full Title: A TACL Phase 1/2 Study of PO Ixazomib in Combination with Chemotherapy for Childhood Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma
    Medical condition: Acute Lymphoblastic Leukemia (ALL) and Lymphoblastic Lymphoma (LLy)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10000845 Acute lymphoblastic leukemia LLT
    20.0 100000004864 10065923 Lymphoblastic lymphoma LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2006-002308-32 Sponsor Protocol Number: P04229 Start Date*: 2007-05-16
    Sponsor Name:Schering-Plough Research Institute, a division of Schering Corporation
    Full Title: A Randomized Placebo-Controlled Efficacy and Safety Study of 1-Year Duration with High and Medium Dose Inhaled Mometasone Furoate/Formoterol Combination Formulation Compared With Formoterol and Hig...
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10009033 Chronic obstructive pulmonary disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) HU (Completed) SK (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2012-001824-36 Sponsor Protocol Number: 201201 Start Date*: 2012-07-12
    Sponsor Name:Medizinsiche Universität Wien, Klinik für Innere Medizin III, Abteilung für Nephrologie und Dialyse
    Full Title: ORAL SODIUM BICARBONATE SUPPLEMENTATION IN PATIENTS WITH CHRONIC METABOLIC ACIDOSIS AND CHRONIC KIDNEY DISEASE
    Medical condition: Patients classified to have chronic kidney disease of stage 3 and 4 and chronic metabolic acidosis (venous serum HCO3- of <21mml/L on 2 separate measurements at least 1 day apart) should be include...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10066569 Chronic acidosis LLT
    14.1 10038359 - Renal and urinary disorders 10064848 Chronic kidney disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002309-30 Sponsor Protocol Number: P04230 Start Date*: 2007-06-18
    Sponsor Name:Schering-Plough Research Institute, a division of Schering Corporation
    Full Title: A Randomized Placebo-Controlled Efficacy and Safety Study of 1-Year Duration with High and Medium Dose Inhaled Mometasone Furoate/Formoterol Combination Formulation Compared With Formoterol and Hig...
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10009033 Chronic obstructive pulmonary disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) NL (Completed) HU (Completed) SK (Completed) EE (Completed)
    Trial results: View results
    EudraCT Number: 2008-005135-15 Sponsor Protocol Number: 8101 colloidAug08 Start Date*: 2009-01-12
    Sponsor Name:University of Nottingham
    Full Title: Do 100 kiloDaltons matter? A prospective randomised double-blind study on the blood volume expanding effects of two different colloids in patients undergoing laparoscopic cholecystectomy
    Medical condition: Patients undergoing laparoscopic cholecystectomy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10006990 Calculus gallbladder LLT
    9.1 10017626 Gallbladder disorder LLT
    9.1 10006992 Calculus in gallbladder LLT
    9.1 10042140 Stone in gallbladder LLT
    9.1 10029543 Non-functioning gallbladder LLT
    9.1 10003643 Atonic gallbladder LLT
    9.1 10017633 Gallbladder inflammation LLT
    9.1 10058468 Laparoscopic surgery LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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